The Roosters try to hold on to their top-eight spot, whereas the Cowboys need to maintain their quantity two slot to lock in a house remaining.
Later the Sharks and Broncos can be hoping to notch straightforward wins in opposition to the lower-ranked Tigers and Knights respectively.
Take a look at all of the reside scores and stats beneath.
Sydney Roosters vs North Queensland Cowboys
Wests Tigers vs Cronulla Sharks
Brisbane Broncos vs Newcastle Knights